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Peter Hersey Selected Research

GSK1210151A

10/2020Co-targeting bromodomain and extra-terminal proteins and MCL1 induces synergistic cell death in melanoma.
8/2015Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling.
11/2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151.
11/2014The epigenetic regulator I-BET151 induces BIM-dependent apoptosis and cell cycle arrest of human melanoma cells.

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Peter Hersey Research Topics

Disease

135Melanoma (Melanoma, Malignant)
01/2022 - 01/2002
52Neoplasms (Cancer)
01/2022 - 10/2002
7Neoplasm Metastasis (Metastasis)
10/2021 - 06/2005
6Disease Progression
09/2017 - 06/2007
5Necrosis
08/2021 - 12/2004
3Fatigue
01/2015 - 06/2009
3Diarrhea
07/2012 - 06/2009
2Fever (Fevers)
01/2022 - 12/2019
2Exanthema (Rash)
07/2012 - 01/2012
2Edema (Dropsy)
07/2012 - 01/2012
2Thrombocytopenia (Thrombopenia)
06/2009 - 10/2006
2Stomach Neoplasms (Stomach Cancer)
02/2009 - 02/2008
2AIDS-Related Complex (ARC)
08/2008 - 02/2008
2Nevus (Nevi)
04/2007 - 10/2006
1Virus Diseases (Viral Diseases)
01/2022

Drug/Important Bio-Agent (IBA)

29Proteins (Proteins, Gene)FDA Link
01/2021 - 07/2003
14Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018 - 05/2003
11pembrolizumabIBA
11/2021 - 07/2013
10Small Interfering RNA (siRNA)IBA
08/2014 - 06/2007
9DNA (Deoxyribonucleic Acid)IBA
08/2021 - 01/2002
9LigandsIBA
10/2012 - 03/2004
8Immune Checkpoint InhibitorsIBA
01/2020 - 07/2013
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2012 - 03/2004
7VemurafenibIBA
01/2020 - 01/2012
7Messenger RNA (mRNA)IBA
01/2013 - 03/2004
7Death Domain ReceptorsIBA
10/2012 - 03/2004
7Docetaxel (Taxotere)FDA Link
12/2010 - 02/2007
6VaccinesIBA
01/2020 - 01/2002
6Histone Deacetylases (Histone Deacetylase)IBA
01/2018 - 04/2004
6CaspasesIBA
01/2018 - 10/2003
6Histone Deacetylase InhibitorsIBA
01/2018 - 10/2003
6TunicamycinIBA
02/2014 - 06/2007
6Endoplasmic Reticulum Chaperone BiPIBA
02/2014 - 10/2007
6Cisplatin (Platino)FDA LinkGeneric
01/2013 - 02/2006
5Biomarkers (Surrogate Marker)IBA
01/2022 - 03/2009
5Pharmaceutical PreparationsIBA
01/2021 - 02/2008
5Dacarbazine (DIC)FDA LinkGeneric
01/2019 - 10/2006
5L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2018 - 10/2006
5Monoclonal AntibodiesIBA
04/2016 - 10/2006
5Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
02/2014 - 08/2007
5ThapsigarginIBA
09/2009 - 10/2007
4trametinibIBA
01/2022 - 07/2012
4Temozolomide (Temodar)FDA LinkGeneric
01/2022 - 06/2007
4Apoptosis Regulatory ProteinsIBA
10/2020 - 10/2003
4GSK1210151AIBA
10/2020 - 11/2014
4Phosphotransferases (Kinase)IBA
11/2017 - 02/2007
4Glucose (Dextrose)FDA LinkGeneric
02/2014 - 10/2007
4PLX 4720IBA
02/2013 - 02/2011
4Biological ProductsIBA
01/2013 - 01/2004
4AntigensIBA
10/2012 - 07/2003
4Taxoids (Taxanes)IBA
12/2008 - 02/2007
3dabrafenibIBA
01/2022 - 03/2012
3Transcription Factors (Transcription Factor)IBA
08/2021 - 06/2007
3Histones (Histone)IBA
12/2020 - 01/2013
3B7-H1 AntigenIBA
10/2018 - 12/2016
3IpilimumabIBA
10/2018 - 01/2012
3AntibodiesIBA
04/2018 - 10/2010
3Mitogen-Activated Protein KinasesIBA
11/2017 - 02/2007
3CytokinesIBA
11/2014 - 02/2004
3Bcl-2-Like Protein 11IBA
11/2014 - 10/2003
3ABT-737IBA
02/2013 - 02/2012
3Phosphatidylinositols (Phosphatidylinositol)IBA
01/2013 - 05/2009
3MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA
01/2012 - 08/2007
3MitogensIBA
01/2012 - 08/2007
3TNF-Related Apoptosis-Inducing LigandIBA
10/2010 - 10/2003
3Vincristine (Oncovin)FDA LinkGeneric
05/2009 - 02/2006
3Protein Isoforms (Isoforms)IBA
03/2008 - 12/2004
3U 0126 (UO 126)IBA
10/2007 - 05/2003
3ParaffinIBA
04/2007 - 12/2004
3suberic bishydroxamateIBA
02/2006 - 10/2003
3Peptides (Polypeptides)IBA
03/2005 - 01/2002
2InflammasomesIBA
01/2022 - 01/2020
2InterferonsIBA
08/2021 - 01/2019
2RNA (Ribonucleic Acid)IBA
08/2021 - 12/2020
2ChromatinIBA
12/2020 - 01/2018
2Histone MethyltransferasesIBA
12/2020 - 01/2015
2Paclitaxel (Taxol)FDA LinkGeneric
01/2019 - 06/2009
2PanobinostatIBA
01/2018 - 08/2015
2ChemokinesIBA
11/2014 - 03/2014
2EnzymesIBA
02/2014 - 01/2012
2obatoclaxIBA
01/2013 - 09/2009
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
07/2012 - 02/2012
2MicroRNAs (MicroRNA)IBA
10/2011 - 09/2011
2oblimersen (G3139)IBA
01/2010 - 10/2006
2X-Box Binding Protein 1IBA
05/2009 - 02/2009
2Indicators and Reagents (Reagents)IBA
10/2008 - 01/2006
2Caspase 8 (Caspase-8)IBA
02/2008 - 10/2003
2Caspase 3 (Caspase-3)IBA
08/2007 - 10/2003
2Formaldehyde (Formol)FDA Link
10/2006 - 12/2004
2Antineoplastic Agents (Antineoplastics)IBA
01/2006 - 10/2003
1Chloroquine (Aralen)FDA LinkGeneric
01/2022
1Lysine (L-Lysine)FDA Link
01/2021
1S63845IBA
10/2020
1ISCOMATRIXIBA
01/2020
1Protein Kinases (Protein Kinase)IBA
01/2020

Therapy/Procedure

33Therapeutics
01/2022 - 01/2002
25Immunotherapy
01/2022 - 01/2002
15Drug Therapy (Chemotherapy)
01/2022 - 01/2002
2Secondary Prevention
01/2015 - 12/2011
2Aftercare (After-Treatment)
03/2012 - 02/2007